彭鹏 教授
博士，博士生导师
山东大学未来计划学者
山东大学齐鲁青年学者
山东省泰山学者青年专家
通讯地址：山东省青岛市滨海公路72号山东大学青岛校区淦昌苑F226
联系电话：+86 156 6278 1483
电子邮箱：pengpeng@sdu.edu.cn
教育经历
2006.9 – 2011.7 北京大学药学院，天然药物及仿生药物国家重点实验室
化学生物学博士（导师：叶新山 教授）
2002.9 – 2006.7 兰州大学化学与化工学院，化学基地班
理学学士（论文指导老师：曹小平教授）
工作经历
2016.6 – 今 山东大学国家糖工程技术研究中心，研究员、教授
2014.2 – 2016.5 Konstanz大学化学系，博士后（合作导师：Richard R. Schmidt 教授）
2012.8 – 2014.2 香港大学化学系，博士后研究助理（合作导师：李学臣 教授）
研究方向与兴趣
新的寡糖化学合成方法的发展。
生物活性寡糖（肿瘤、病毒、细菌相关糖抗原）的合成及药物活性评价。
以糖类化合物为基础的抗菌、抗癌疫苗的研制（设计、合成及评价）。
科研项目
（1）国家自然科学基金重大研究计划（培育类）项目，主持
（2）国家自然科学基金面上项目，主持
（3）国家自然科学基金青年项目，主持
（4）山东省自然科学基金项目，主持
（5）山东省重点研发计划项目，主持
（6）国家重点研发计划，子课题负责人
代表性论文
1. Yuanyuan Li, Haoru Zhuang, Xuerui Tao, Yingguo Liu, Tianlu Li, Peng Peng* Convergent synthesis of steviol glycosides rebaudioside A and M. Carbohydr. Res. 2025, 552, 109446.
2. Miaomiao Zhang, Jinjuan Gan, Peng Peng* Tianlu Li* Stereoselective Synthesis of 1,2-cis O-linked Glycosyl Amino Acids via Additive-Modulation for Glycopeptide Synthesis. Chem. Eur. J. 2025, e202404786.
3. Miaomiao Zhang, Haoru Zhuang, Yongshun Qiu, Yuanyuan Li, Shuting Liu, Tong Li, Tianlu Li, Peng Peng* Mercury(II) triflate catalyzed direct α-stereoselective synthesis of 2-deoxyglycosides from glycals. J. Carbohydr. Chem. 2024, 43, 289-301.
4. Tianlu Li, Tong Li, Yue Yang, Haoru Zhuang, Jianwu Lv, Ning Zhou, Miaomiao Zhang, Fengshan Wang, Yiqun Geng, Richard R. Schmidt*, Peng Peng* Concise Synthesis of Lactococcus garvieae Lipoteichoic Acids Through an Additive-Modulated Preactivation Protocol and the Immunological Studies. CCS Chem. 2024, 6, 403-414.
5. Yue Yang, Tong Li, Huiran Hao, Ju-Zheng Sheng, Tianlu Li*, Peng Peng* Convergent Synthesis of Glycoalkaloids Solasonine and its Saponin Derivative. Chem. Commun. 2024, 60, 9753-9756.
6. Tianlu Li, Miaomiao Zhang, Panpan Lv, Yue Yang, Richard R. Schmidt*, Peng Peng* Synthesis of Core M3 Matriglycan Constituents via an Additive-Controlled 1,2-cis-Xylopyranosylation with O-Xylosyl Imidates as Donors. J. Org. Chem. 2024, 89, 804-809.
7. Tianlu Li, Tong Li, Yue Yang, Yongshun Qiu, Yingguo Liu, Miaomiao Zhang, Haoru Zhuang, Richard R. Schmidt*, Peng Peng* Reaction Rate and Stereoselectivity Enhancement in Glycosidations with O-Glycosyl Trihaloacetimidate Donors due to Catalysis by a Lewis Acid–Nitrile Cooperative Effect. J. Org. Chem. 2024, 89, 7865-7876.
8. Dengxian Fu, Shuxin Zhang, Bingbing Xu, Peng Peng, Qian Wan*, Jing Zeng* Selective Reduction Leading to 3,5-cis-3-Aminosugars: Synthesis and Stereoselective Glycosylation. J. Org. Chem. 2023, 88, 727-731.
9. Miaomiao Zhang, Tianlu Li, Peng Peng* Recent Development in Additive Modulated Stereoselective Glycosidation Reactions. J. Carbohydr. Chem. 2022, 40, 339-360.
10. Tianlu Li, Tong Li, Youqin Zhang, Richard R. Schmidt*, Peng Peng* Preparation of Tea Aroma Precursor Glycosides: An Efficient and Sustainable Approach via Chemical Glycosidation. J. Agric. Food. Chem. 2022, 70, 2320-2327.
11. Tianlu Li*, Youqin Zhang, Tong Li, Haoru Zhuang, Fengshan Wang, Ning Wang, Richard R. Schmidt, Peng Peng. Divergent Synthesis of Core m1, Core m2 and Core m3 O-Mannosyl Glycopeptides via a Chemoenzymatic Approach. Chin. J. Chem. 2022, 40, 1571-1577.
12. Tianlu Li*, Tong Li, Yajing Sun, Yue Yang, Panpan Lv, Fengshan Wang, Hongxiang Lou, Richard R. Schmidt*, Peng Peng*. Regioselective Benzoylation of Unprotected β-glycopyranosides with Benzoyl Cyanide and an Amine Catalyst – Application to Saponin Synthesis. Org. Chem. Front. 2021, 8, 260-265.
13. Tong Li+, Tianlu Li+, Haoru Zhuang, Fengshan Wang, Richard R. Schmidt*, Peng Peng*, O-Glycosyl Trichloroacetimidates as Glycosyl Donors and Platinum(IV) Chloride as a Dual Catalyst Permitting Stereo- and Regioselective Glycosidations. ACS Catal. 2021, 11, 10279-10287.
14. Wei Song, Yong Sun, Lintao Xu, Yajing Sun, Tianlu Li, Peng Peng*, Hongxiang Lou, Synthesis of nature product kinsenoside analogues with anti-inflammatory activity. Bioorg. Med. Chem. 2021, 29, 115854.
15. Wenzheng Wang, Yajing Sun, Peng Peng, Guofeng Gu, Guoying Du, Li Xu*, Xiao, Min* Two-Step Enzymatic Conversion of Rebaudioside A into a Mono-α-1,4-Glucosylated Rebaudioside A Derivative. J. Agric. Food. Chem. 2021, 69, 2522-2530.
16. Tianlu Li+, Tong Li+, Michael Linseis+, Fengshan Wang, Rainer F. Winter, Richard R. Schmidt*, Peng Peng*. Catalytic Regioselective Benzoylation of 1,2-trans-Diols in Carbohydrates with Benzoyl Cyanide: The Axial Oxy Group Effect and the Action of Achiral and Chiral Amine Catalysts. ACS Catal. 2020, 10, 11406-11416.
17. Tong Li+, Tianlu Li+, Tongxiao Cui, Yajing Sun, Fengshan Wang, Hongzhi Cao, Richard R. Schmidt*, Peng Peng*. Regioselective One-Pot Benzoylation of Triol and Tetraol Arrays in Carbohydrates. Org. Lett. 2018, 20, 3862-3865.
18. Peng Peng, Richard R. Schmidt* Acid–Base Catalysis in Glycosidations: A Nature Derived Alternative to the Generally Employed Methodology. Acc. Chem. Res. 2017, 50, 1171-1183.
19. Peng Peng, Michael Linseis, Rainer F. Winter and Richard R. Schmidt* Regioselective Acylation of Diols and Triols: The Cyanide Effect J. Am. Chem. Soc. 2016, 138, 6002-6009.
20. Peng Peng, Richard R. Schmidt* An Alternative Reaction Course in O-glycosidation with O-glycosyl Trichloroacetimidates as Glycosyl Donors and Lewis Acidic Metal Salts as Catalyst: Acid-Base Catalysis with Gold Chloride-Glycosyl Acceptor Adducts J. Am. Chem. Soc. 2015, 137, 12653-12659.
21. Peng Peng, Yiqun Geng, Göttker-Schnetmann, Inigo and Richard R. Schmidt* 2-Nitro-thioglycosides: α- and β-Selective Generation and Their Potential as β-Selective Glycosyl Donors Org. Lett. 2015, 17, 1421-1424.
22. Peng Peng, Han Liu, Jianzhi Gong, John M. Nicholls, Xuechen Li* A Facile Synthesis of Sialylated Oligolactosamine Glycans from Lactose via the Lafont Intermediate Chem. Sci. 2014, 5, 3634-3639.
23. Peng Peng, De-Cai, Xiong, Xin-Shan Ye* Ortho-Methylphenylthioglycosides as Glycosyl Building Blocks for Preactivation-based Oligosaccharide Synthesis Carbohydr. Res. 2014, 384, 1-8.
24. Peng Peng, Xin-Shan Ye* O,O-Dimethylthiophosphonosulfenyl Bromide-silver Triflate: a New Powerful Promoter System for the Preactivation of Thioglycosides Org. Biomol. Chem. 2011, 9, 616-622.
25. Yinping Li, Weiying Hong, Henan Zhang, Tiantian Zhang, Zhiyong Chen, Shiling Yuan, Peng Peng,* Min Xiao,* Li Xu* Photothermally triggered cytosolic drug delivery of glucose functionalized polydopamine nanoparticles in response to tumor microenvironment for the GLUT1-targeting chemo-phototherapy. J. Control release 2020, 317, 232-245.
26. Jinfeng Ye, Xian -Wei Liu, Peng Peng, Wen Yi, Xi Chen, Fengshan Wang, Hongzhi Cao * Diversity-Oriented Enzymatic Modular Assembly of ABO Histo-blood Group Antigens. ACS Catal. 2016, 6, 8140-8144.
学术兼职
中国化学会糖化学专业委员会委员，
中国生化制药工业协会糖类药物分会第一届专家委员会委员，
中国生物化学与分子生物学会糖复合物专业分会第一届青年委员会委员，
中国疫苗行业协会糖疫苗专业委员会委员，
国家药品监督管理局糖药物质量研究与评价重点实验室秘书，
济南市海右产业领军人才，
国家糖工程技术研究中心学术委员会委员
