|
Peng Peng |
Tel: 15662781483 |
Professor |
E-mail: pengpeng@sdu.edu.cn |
Address: 72 Binhai Road, Qingdao, 266237, China |
Education
Degree |
Date |
Affiliation |
Major |
PhD |
2011 |
Peking University |
Chemical Biology |
Master |
Bachelor |
2006 |
Lanzhou University |
Chemistry |
Research Experience
Date |
Affiliation |
Position |
2016-Present |
National Glycoengineering Research Center, Shandong University |
Professor |
2014-2016 |
University of Konstanz |
Post-doctoral Fellow |
2012-2014 |
The University of Hong Kong |
Post-doctoral Fellow |
Research Interests
Carbohydrate chemistry
Development of novel methodology towards complex carbohydrate synthesis
reparation of oligosaccharides and glycoconjugates
Representative Publications
1. Tong, Li‖;Tianlu, Li‖; Haoru, Zhuang; Fengshan, Wang; Richard, R. Schmidt; Peng, Peng, O-Glycosyl Trichloroacetimidates as Glycosyl Donors and Platinum(IV) Chloride as a Dual Catalyst Permitting Stereo- and Regioselective Glycosidations. ACS Catalysis 2021, 11, 10279-10287.(‖equal contribution)
2. Tianlu, Li,* Tong Li, Yajing Sun, Yue Yang, Panpan Lv, Fengshan Wang, Hongxiang Lou, Richard R. Schmidt* and Peng Peng* Regioselective Benzoylation of Unprotectedβ-Glycopyranosides with Benzoyl Cyanide and an Amine Catalyst–Application to Saponin Synthesis, Organic Chemistry Frontiers 2021, 8, 260-265.
3. Tianlu, Li‖; Tong, Li‖; Michael, Linseis‖; Fengshan, Wang; Rainer, F. Winter; Richard, R. Schmidt; Peng, Peng, Catalytic Regioselective Benzoylation of 1,2-trans-Diols in Carbohydrates with Benzoyl Cyanide: The Axial Oxy Group Effect and the Action of Achiral and Chiral Amine Catalysts. ACS Catalysis 2020,10, 11406-11416. (‖equal contribution)
4. Tianlu, Li; Weizhun, Yang; Sherif, Ramadan; Xuefei, Huang* Synthesis of O-Sulfated Human Syndecan-1-like Glyco-polypeptides by Incorporating Peptide Ligation and O-Sulfated Glycopeptide Cassette Strategies. Organic Letters 2020, 22, 6429-6433.
5. Tong, Li‖;Tianlu, Li‖; Tongxiao, Cui; Yajing, Sun; Fengshan, Wang; Hongzhi, Cao; Richard, R. Schmidt*; Peng, Peng* Regioselective One-Pot Benzoylation of Triol and Tetraol Arrays in Carbohydrates.Organic Letters 2018, 20, 3862-3865. (‖equal contribution)
6. Peng Peng, Richard R. Schmidt* Acid–Base Catalysis in Glycosidations: A Nature Derived Alternative to the Generally Employed Methodology. Acc. Chem. Res. 2017, 50, 1171-1183.
7. Peng Peng, Michael Linseis, Rainer F. Winter, Richard R. Schmidt* Regioselective Acylation of Diols and Triols: The Cyanide Effect J. Am. Chem. Soc. 2016, 138, 6002-6009.
8. Peng Peng, Richard R. Schmidt* An Alternative Reaction Course in O-glycosidation with O-glycosyl Trichloroacetimidates as Glycosyl Donors and Lewis Acidic Metal Salts as Catalyst: Acid-Base Catalysis with Gold Chloride-Glycosyl Acceptor Adducts J. Am. Chem. Soc. 2015, 137, 12653-12659.
9. Peng Peng, Yiqun Geng, Göttker-Schnetmann, Inigo and Richard R. Schmidt* 2-Nitro-thioglycosides: α- and β-Selective Generation and Their Potential as β-Selective Glycosyl Donors Org. Lett. 2015, 17, 1421-1424.
10. Peng Peng+, Han Liu+, Jianzhi Gong, John M. Nicholls, Xuechen Li* A Facile Synthesis of Sialylated Oligolactosamine Glycans from Lactose via the Lafont Intermediate Chem. Sci. 2014, 5, 3634-3639.
11. Peng Peng, De-Cai, Xiong, Xin-Shan Ye* Ortho-Methylphenylthioglycosi des as Glycosyl Building Blocks for Preactivation-based Oligosaccharide Synthesis Carbohydr. Res. 2014, 384, 1-8.
12. Peng Peng, Xin-Shan Ye* O,O-Dimethylthiophosphonosulfenyl Bromide-silver Triflate: a New Powerful Promoter System for the Preactivation of Thioglycosides Org. Biomol. Chem. 2011, 9, 616-622.
13. Yinping Li, Weiying Hong, Henan Zhang, Tiantian Zhang, Zhiyong Chen, Shiling Yuan, Peng Peng,* Min Xiao,* Li Xu* Photothermally triggered cytosolic drug delivery of glucose functionalized polydopamine nanoparticles in response to tumor microenvironment for the GLUT1-targeting chemo-phototherapy. J. Control. Release 2020, 317, 232-245.
14. Wei Song+, Yong Sun+, Lintao Xu, Yajing Sun, Tianlu Li, Peng Peng,* Hongxiang Lou* Synthesis of nature product kinsenoside analogues with anti-inflammatory activity Bioorg. Med. Chem. 2021, 29, 115854.
15. Jinfeng Ye, Xian -Wei Liu, Peng Peng, Wen Yi, Xi Chen, Fengshan Wang, Hongzhi Cao* Diversity-Oriented Enzymatic Modular Assembly of ABO Histo-blood Group Antigens. ACS Catal. 2016, 6, 8140-8144.
Honors and Awards
中国生物化学与分子生物学会糖复合物专业委员会第一届青年工作委员会委员
中国生化制药工业协会糖类药物分会第一届专家委员会委员
国家糖工程技术研究中心学术委员会委员
Patents
一种糖苷化反应催化剂、糖苷化方法和应用，国家发明专利，202110864797X
一种N-乙酰基-L-酪氨酰-L-精氨酸十六烷基酯的合成方法，国家发明专利，2021102114492
一种茶叶香料前体糖苷及其合成方法，国家发明专利，2020102370352
一种O‐甘露聚糖核心结构的合成方法，国家发明专利，ZL201910309945.4
