|
Xianwei Liu |
Tel: 0532-58631415 |
Associate Professor |
Supervisor of Doctor's Candidates |
E-mail: xianweiliu@sdu.edu.cn |
Address: National Glycoengineering Research Center Shandong University, Qingdao Room 228, Block F, Gan chang Courtyard Qingdao campus of Shandong University, 72 Binhai Road Jimo District, Qingdao, Shandong, 266237 China |
Education
Degree |
Date |
Affiliation |
Major |
PhD |
2009.6 |
Shandong University |
Microbiology |
Master |
|
|
|
Bachelor |
2003.6 |
Shanxi University |
Biological Sciences |
Research Experience
Date |
Affiliation |
Position |
2016.9- |
Shandong University |
Assoc. Prof. |
2009.9-2016.9 |
Shandong University |
Lecturer |
2007.2-2009.2 |
Ohio State University, USA |
Visiting Scholar |
Research Interests
Biocatalysis including enzyme identification and engineering, chemoenzymatic synthesis andsyntheticbiology of glycan and glycoconjugates; Chemical biology including labeling and modification of glycan and proteins for biomarker detection and medical applications.
Representative Publications
1. Jing Liu, Xuefei Yin, Zitao Li, Xiaocong Wu, Zhaoxuan Zheng, Junqiang Fang, Guofeng Gu, Peng G. Wang, Xianwei Liu*. 2021, Facile enzymatic synthesis of diverse naturally-occurring β-D-mannopyranosides catalyzed by glycoside phosphorylases. ACS Catalysis, 11(5): 2763-2768.
2. Jinfeng Ye#, Xian-wei Liu#, Peng Peng, Wen Yi, Xi Chen, Fengshan Wang, Hongzhi Cao*. 2016. Diversity-Oriented Enzymatic Modular Assembly of ABO Histo-blood Group Antigens. ACS Catalysis, 6 (12): 8140-8144.
3. Wenjing Shang, Yafei Zhai, Zhongrui Ma, Gongjin Yang, Yan Ding, Donglei Han, Jiang Li, Houcheng Zhang, Jun Liu, Peng George Wang, Xian-wei Liu*, Min Chen*. 2016. Production of human blood group B antigen epitope conjugated protein in Escherichia coli and utilization of the adsorption blood group B antibody. Microbial Cell Factories, 15: 138.
4. Yafei Zhai, Donglei Han, Ying Pan, Shuaishuai Wang, Junqiang Fang, Peng Wang, Xian-wei Liu*. 2015. Enhancing GDP-fucose production in recombinant Escherichia coli by metabolic pathway engineering. Enzyme and Microbial Technology, 69: 38-45.
5. Junqiang Fang, Mengyang Xue, Guofeng Gu, Xian-wei Liu*, Peng George Wang. 2013. A chemoenzymatic route to synthesize unnatural sugar nucleotides using a novel N-acetylglucosamine-1-phosphate pyrophosphorylase from Camphylobacter jejuni NCTC 11168. Bioorganic & Medicinal Chemistry Letters, 23(15): 4303-4307.
6. Yafei Zhai, Min Liang, Junqiang Fang, Xiaoyue Wang, Wanyi Guan, Xian-wei Liu*, Peng Wang, Fengshan Wang. 2012. NahK/GlmU fusion enzyme: Characterization and one-step enzymatic synthesis of UDP-N-acetylglucosamine. Biotechnology Letters, 34(7): 1321-1326.
7. Min Liang, Min Chen, Xinying Liu, Yafei Zhai, Xian-wei Liu*, Houcheng Zhang*, Min Xiao, Peng Wang. 2012. Bioconversion of D-galactose to D-tagatose: continuous packed bed reaction with an immobilized thermostable L-arabinose isomerase and efficient purification by selective microbial degradation. Applied Microbiology and Biotechnology, 93(4): 1469-1474.
8. Xian-wei Liu, Chengfeng Xia, Lei Li, Wan-yi Guan, Nicholas Pettit, Hou-cheng Zhang, Min Chen*, Peng George Wang. 2009. Characterization and synthetic application of a novel β1,3-galactosyltransferase from Escherichia coli O55:H7. Bioorganic & Medicinal Chemistry, 17(14): 4910-4915.
9. Wen Yi, Xianwei Liu, Yanhong Li, Jianjun Li, Chengfeng Xia, Guangyan Zhou, Wenpeng Zhang, Wei Zhao, Xi Chen, Peng George Wang*. 2009. Remodeling bacterial polysaccharides by metabolic pathway engineering. Proceedings of the National Academy of Sciences of the United States of America, 106(11): 4207-4212.
Patents
1. Xianwei Liu, Zitao Li, Jing Liu, Xiaocong Wu, Zhaoxuan Zheng. A method for the recombinant production of microbial transglutaminase. China Patent Application, NO. 202110038716.0
2. Xianwei Liu, Zhaoxuan Zheng, Xiaocong Wu, Jing Liu, Zitao Li, Jing Zhang. A monosaccharide kinase catalyzing the synthesis of L-arabinose 1-phosphate and its application to the preparation of activated arabinose. China Patent Application, NO. 202011058835.4
