|
Name: Bin Sun |
Tel: 18615617661 |
Title: Associate Professor |
Supervisor: Master advisor |
E-mail: sunbin@sdu.edu.cn |
Address:Western Wenhua Rd 44#, Jinan City, Shandong Province |
Education
Degree |
Date |
Affiliation |
Major |
PhD |
2005-2010 |
School of Pharmacy,Shandong University |
Medicinal Chemistry |
Master |
|
|
|
Bachelor |
2001-2005 |
School of Pharmacy,Shandong University |
Pharmacy |
Research Experience
Date |
Affiliation |
Position |
2010-2018 |
National Glycoengineering Research Center, Shandong University |
Assistant Professor |
2018-2021 |
National Glycoengineering Research Center, Shandong University |
Associate Professor |
Research Interests
Total synthesis of natural products and derivatives as anticancer and antifungal agents.
Representative Publications
1. Xiaoyu Zhao#,Bin Sun#, Hongbo Zheng, Jun Liu, Xiaoning Wang*, Hongxiang Lou*, Synthesis and biological evaluation of 6-hydroxyl C-aryl glucoside derivatives as novel sodium glucose co-transporter 2 (SGLT2) inhibitors,Bioorganic & Medicinal Chemistry Letters,2018, 28: 2201-2205.
2. Changyi Cui, Jun Liu, Hongbo Zheng, Xueyang Jin, Xiaoyu Zhao, Wenqiang Chang,Bin Sun*, Hongxiang Lou*, Diversity-oriented synthesis of pyrazoles derivatives from flavones and isoflavones leads to the discovery of promising reversal agents of fluconazole resistance inCandida albicans,Bioorganic & Medicinal Chemistry Letters,2018, 28: 1545-1549.
3. Jun Liu#,Bin Sun#, Xiaoyu Zhao, Jie Xing, Yanhui Gao, Wenqiang Chang, Jianbo Ji, Hongbo Zheng, Changyi Cui, Aiguo Ji*, Hongxiang Lou*, Discovery of potent orally active protase-activated receptor 1 (PAR1) antagonist based on andrographolide,Journal of Medicinal Chemistry,2017, 60 (16): 7166-7185
4.Bin Sun#, Jun Liu#, Yun Gao, Hongbo Zheng, Lin Li, Qingwen Hu, Huiqing Yuan, Hongxiang Lou*, Design, synthesis, and biological evaluation of nitrogen-containing macrocyclic bisbibenzyl derivatives as potent anticancer agents by targeting the lysosome,European Journal of Medicinal Chemistry,2017, 136:603-618
5.Bin Sun, Lin Li, Qingwen Hu, Hongbo Zheng, Hui Tang, Huanmin Niu, Huiqing Yuan, Hongxiang Lou*, Design, synthesis, biological evaluation and molecular modeling study of novel macrocyclic bisbibenzyl analogues as antitubulin agents,European Journal of Medicinal Chemistry,2017, 129:186-208
6.Bin Sun, Ming Zhang, Ying Li, Qingwen Hu, Hongbo Zheng, Wenqiang Chang, Hongxiang Lou*, Synthesis of riccardin D derivatives as potent antimicrobial agents,Bioorganic & Medicinal Chemistry Letters,2016, 26 (15): 3617-3620
7.Bin Sun, Lin Li, Qingwen Hu, Fei Xie, Hongbo Zheng, Huanmin Niu, Huiqing Yuan, Hongxiang Lou*, Design, synthesis and biological evaluation of novel macrocyclic bisbibenzyl analogues as tubulin polymerization inhibitors,European Journal of Medicinal Chemistry,2016, 121: 484-499
