Photo:
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Name: Lan JIN |
Tel:0532-58631418 |
Title: Associate Professor |
Supervisor: Master |
E-mail: lanjin@sdu.edu.cn |
Address: No.72 Binhai Road, Shandong University (Qingdao), Qingdao, Shandong, P. R.China |
Education
Degree |
Date |
Affiliation |
Major |
PhD |
2003.10-2007.06 |
University of Edinburgh |
Biophysical Chemistry |
Master |
|
|
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Bachelor |
1999.08-2003.07 |
Liaoning University |
Applied Chemistry |
Research Experience
Date |
Affiliation |
Position |
2007.06-2008.07 |
University of Edinburgh |
Post Doc |
2008.08- |
Shandong University |
Associate Professor |
Research Interests
1. Conformation of oligosaccharides using NMR;
2. Structure-activity relationship between oligosaccharides and proteins;
3. Structural similarity assessment of glycosaminoglycans related carbohydrate drugs and polypeptide drugs.
Representative Publications
1. A. Sheng, Q. Chen, M. Yu, R. Xiao, T. Zhang, Z. Wang, R. J. Linhardt, X. Sun*, L. Jin*, L. Chi*, Coupling liquid chromatography and tandem mass spectrometry to electrophoresis for in-depth analysis of glycosaminoglycan drugs: Heparin and the Multicomponent Sulodexide, Analytical Chemistry, 2021, 93: 1433-1442.
2. C. Bu and L. Jin*, NMR Characterization of the Interactions Between Glycosaminoglycans and Proteins, Frontiers in Molecular Biosciences, 2021, 8: 646808.
3. S. Xie, Y. Guan, P. Zhu, F. Li, M. Yu, R. J. Linhardt, L. Chi*, L. Jin*, Preparation of low molecular weight heparins from bovine and ovine heparins using nitrous acid degradation, Carbohydrate Polymers, 2018, 197: 83-91.
4. X. Sun, A. Sheng, X. Liu, F. Shi, L. Jin, S. Xie, F. Zhang, R.J. Linhardt, L. Chi*, Comprehensive identification and quantitation of basic building blocks for low-molecular weight heparin, Analytical Chemistry, 2016, 88: 7738-7744.
5. X. Cao, Q. Lv, D. Li, H. Ye, X. Yan, X. Yang, H.Gan, W. Zhao, L. Jin*, P. Wang*, J. Shen*, Direct C5-isomerization approach to L-iduronic acid derivatives, Asian Journal of Organic Chemistry, 2015, 9: 899-902.
6. X. Meng, W. Yao, J. Cheng, X. Zhang, L. Jin, H. Yu, X. Chen, F. Wang, H. Cao, Regioselective chemoenzymatic synthesis of ganglioside disialyl-tetrasaccharide epitopes, Journal of the American Chemical Society, 2014, 136: 5205-5208.
7. D. Li, L. Chi, L. Jin, X. Xu, X. Du, S. Ji, L. Chi*, Mapping of low molecular weight heparins using reversed phase ion pair liquid chromatography-mass spectrometry, Carbohydrate Polymers, 2014, 99: 339-344.
8. L. Jin, M. Hricovíni, J. A. Deakin, M. Lyon, D. Uhrín, Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin, Glycobiology, 2009, 19: 1185-1196.
9. L. Jin, P. E. Barran, J. A. Deakin, M. Lyon, D. Uhrín, Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling, PhysChemChemPhys, 2005, 7: 3464-3471.
